Prenatal Exposure to Bisphenol A: Implications for Autism Spectrum Disorders

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is very common today. Endocrine disruptors, along with genetic and environmental factors, also influence this condition. These endocrine disruptors affect the functioning of hormones. Bisphenol A (BPA) is one of these endocrine disruptors. Accumulation or exposure to BPA can lead to fetal growth restrictions, neurological disorders, and various other conditions. Infants and young children are more sensitive to these pollutants compared to adults. Babies are exposed to these pollutants in the womb through the placenta. As a result, the endocrine system, as well as neurological, growth, and developmental processes, are significantly affected, leading to conditions such as ASD during growth. Autism spectrum disorder has a profound impact on both the individual and their family. However, ASD is not only caused by such pollutants but also by a variety of genetic and biological factors. In individuals with ASD, it may manifest as repetitive behaviors, communication difficulties, and social deficits. In this review, the following topics have been discussed: the effects of BPA on fetal development, its potential role in ASD, and other contributing genetic and biological factors.

Cite this article as: Bulut MS, Erbaş O. Prenatal Exposure to Bisphenol A: Implications for Autism Spectrum Disorders. JEB Med Sci 2024;5(3):210-213.

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

The authors received no financial support for the research and/or authorship of this article.