Bahar Işık1,Oytun Erbaş2

1Binali Yıldırım University Faculty of Medicine, Mengücek Gazi Training and Research Hospital, Department of Emergency Medicine, Erzincan, Türkiye
2ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Türkiye

Keywords: Antidepressant treatment, anxiety, cardiovascular disease, COVID-19, depression


The relationship between cardiovascular diseases (CVD) and psychiatric diseases is bidirectional and these two common conditions can occur together. Depression is thought to act as a risk factor in the occurrence and progression of CVD in this association. In this review, the studies examining the interaction between CVD and depression and the pathogenesis of this interaction will be reviewed. The emphasis will be on whether depression is a modifiable factor in CVD and whether its treatment can improve survival. We also aim to draw attention to how depression, which is already on the rise in the general population after the coronavirus disease 2019 (COVID-19) pandemic, has changed with CVD and COVID-19.

Cite this article as: Işık B, Erbaş O. Depression and Cardiovascular Disease: A Mutual Relationship. JEB Med Sci 2023;4(1):21-27.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.