Bioinformatics Approaches to Cancer Research
Semanur Ataş1, Gizem Demir1, Mazhar Özkan2, Oytun Erbaş1
1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Türkiye
2Tekirdağ Namık Kemal University, Faculty of Medicine, Department of Anatomy, Tekirdağ, Türkiye
Keywords: Bioinformatics, cancer, cancer genome atlas, epigenetic, genomic sequence, proteomic analysis
Abstract
In the investigation of tumor progression, genomic and epigenetic analyses play equal roles. Proteomic analyses play a significant role in the discovery of biological markers in cancer research. The Cancer Genome Atlas was made possible by genomic sequencing research. In this manner, any variations in the cancer genome can be identified by comparing the genetic sequences of cancer tissue and healthy tissues. In light of this research, systems biology analysis enables the identification of the medication targets as well as their impact on the pathogen and adverse effects on healthy cells. This review aims to highlight the significance of bioinformatics in a variety of cancer investigations, including the identification of malignant cells, customization of cancer genome analyses, and detection of metastasis formation.
Cite this article as: Ataş S, Demir G, Özkan M, Erbaş O. Bioinformatics Approaches to Cancer Research. JEB Med Sci 2022;3(3):246-252.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.