Influence of Cholesterol on Cancer Progression

Tuğçe Uygur1, Züleyha Pestil2, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Türkiye
2Pendik Veterinary Control Institute, İstanbul, Türkiye

Keywords: Cancer, cancer signaling pathways, cholesterol, high-density lipoprotein, low-density lipoprotein

Abstract

Cholesterol is a form of lipids, just as fats are and an essential component of cell membranes that are required for the synthesis of fat-soluble vitamins and steroid hormones such as estradiol, cortisol, progestins and testosterone, and bile acids. High-density lipoprotein and low-density lipoprotein (LDL), which are the most commonly known types of cholesterol, cause various diseases in the body. The LDL cholesterol raises the risk of breast, prostate, testicular, uterine, ovarian, and colorectal cancers and promotes cancer by activating several signaling pathways. This review discusse

Cite this article as: Uygur T, Pestil Z, Erbaş O. Influence of Cholesterol on Cancer Progression. JEB Med Sci 2022;3(3):213-220.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.