Hadi Sasani1, Oytun Erbaş2

1Tekirdağ Namık Kemal University, Faculty of Medicine, Department of Radiology, Tekirdağ, Turkey
2ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Turkey

Keywords: Central nervous system, magnetic resonance imaging, microglia, neuroinflammatory disorders, positron-emission tomography


Microglia are important in the development, homeostasis, and disorders of the central nervous system. Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis, as well as autism, severe depression, and schizophrenia, have all been related to microglia-derived neuroinflammation. Imaging techniques such as magnetic resonance imaging and positron emission tomography can detect neuroinflammation. The purpose of this review was to examine the role of microglia in neurodegenerative disorders, with a focus on imaging.

Cite this article as: Sasani H, Erbaş O. Microglial Effects on Psychiatric Disorders. JEB Med Sci 2022;3(1):26-34.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.