The Complement System During SARS-CoV-2 Infection

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly pathogenic coronavirus that posing a threat to human health and public safety. SARS-CoV-2, which comes from the same family as SARS-CoV and the Middle East respiratory syndrome-related coronavirus (MERS-CoV), has similar characteristics with them, as well as a different protein structure than them, which explains that it causes a larger epidemic than the SARS and MERS virus. It is aimed to stop the epidemic by examining the activities performed by SARS-CoV-2 in the cell and after its entry into the cell. Angiotensin-converting enzyme 2 (ACE2), the input mechanism of SARS-CoV-2, is important in this regard. A defense mechanism against SARS-CoV-2 is developed when it is introduced into our bodies. Complement system constitutes responses for this infection. In this review, the relationship between the complement system and SARS-CoV-2 was discussed.

Cite this article as: Gümüş G, Erbaş O. The Complement System During SARS-CoV-2 Infection. JEB Med Sci 2021;2(3):436-440.

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

The authors received no financial support for the research and/or authorship of this article.