Aylin Kayaaltı1, Berzah Güneş1, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Turkey

Keywords: Central nervous system, neurotransmitters, psychosis, schizophrenia, synaptic vesicle protein 2A


Schizophrenia (SCZ) is a serious mental disorder that affects several different people all around the world. There are lots of different causes of SCZ meanwhile the exact reason is still unknown. Synaptic vesicle protein 2A (SV2A) is a gene thought to be responsible for neurotransmission and some neurotransmitters which are related to SCZ. Although there is not a direct connection between them, recent studies show that there may be an interaction that is hopeful for the treatment of SCZ. In this review SCZ, its causes and treatments, SV2A and its roles, and the connection between SCZ and SV2A were discussed.

Cite this article as: Kayaaltı A, Güneş B, Erbaş O. Synaptic Vesicle Protein 2A:Basic Facts and Roles in Schizophrenia JEB Med Sci 2021;2(3):358-364.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.