Fatty Liver Disease: Diagnosis and Treatment

Edanur Topal1, Kader Aydemir1, Özge Çağlar2,3, Begüm Arda1, Onur Kayabaşı1, Manolya Yıldız1, Elif Özyılmaz3, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Turkey
2Selçuk University, Faculty of Science, Department of Chemistry, Konya/Turkey
3Selçuk University, Faculty of Science, Department of Biochemistry, Konya/Turkey

Keywords: Alcohol, alcoholic fatty liver disease, fructose, liver, non-alcoholic fatty liver disease

Abstract

The liver is the largest organ of our body, which plays a role in the physiological process in the body and is most exposed to toxins. The liver's functions are essential for life since it is involved in macronutrient metabolism. Fatty diets, excessive alcohol consumption, sedentary lifestyles, ready-made foods and beverages, and fructose metabolism in the liver are all factors that contribute to liver fat. In the advanced stage of fatty liver, changes in liver cells, cirrhosis, and hepatocellular carcinoma, which rank first in the world in terms of mortality, are seen. Therefore, current treatments and future approaches to fatty liver research are of tremendous interest. The results of investigations looking into the causes and current treatments for alcoholic liver disease and non-alcoholic fatty liver disease were compiled in this review.

Cite this article as: Topal E, Aydemir K, Çağlar Ö, Arda B, Kayabaşı O, Yıldız M, Özyılmaz E, Erbaş O. Fatty Liver Disease: Diagnosis and Treatment. JEB Med Sci 2021;2(3):343-357.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.