Alper Kurt1, Recep Tayyip Özbek1, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Turkey

Keywords: Age-related macular degeneration, Argus II, microelectrode, retinal implant, retinal prosthesis, retinitis pigmentosa

Abstract

Nowadays, millions of people experience vision loss due to diseases such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD). These diseases can be treated with methods such as gene exchange therapy when diagnosed early. However, retinal implants come into play as a solution for many patients. In this review, retinal implants were examined in two main groups, as Epiretinal implants and Subretinal implants. While Argus II, intelligent medical implants (IMI), EPI-RET3 retinal prosthesis implants were reviewed under the epiretinal title, Alpha IMS and AMS, PRIMA retinal implant, and Boston retinal implant were reviewed in detail under the Subretinal title. In addition, the benefits and disadvantages of retinal implants, as well as the components they include and the studies that have been conducted with these implants, are discussed in this article. Even though retinal implants have been studied for many years, they still have serious shortcomings and negative effects. Many patients with vision loss will have great hope in the near future if these flaws and negative effects are solved.

Cite this article as: Kurt A,Özbek RT, Erbaş O. Systematic Review of Novel Advances in Epiretinal and Subretinal Prosthesis. JEB Med Sci 2021;2(3):326-335.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.