Epidermodysplasia Verruciformis
Mine Ün1, Osman Bahadır Durmaz2, Elif Köylüoğlu2
1Istanbul Aydın University Faculty Medicine, Istanbul, Turkey
2Biruni University Faculty Medicine, Istanbul, Turkey
Keywords: Carcinoma, epidermodysplasia verruciformis, human papilloma viruses
Abstract
Epidermodysplasia verruciformis (UV) is an extremely rare skin disease with autosomal recessive inheritance. This disease is because of susceptibility to certain types of human papilloma virus and mutations of two genes named EVER1/ TMC6 and EVER2/TMC8. Epidermodysplasia verruciformis is characterized by various skin lesions, such as flat warts and reddish papules, which have been seen since childhood. There is a high risk of these lesions becoming malignant in the areas exposed to UV radiation in the following years. This transformation, usually seen in the fourth decade of life, is most commonly associated with squamous cell carcinoma. Although various treatment methods have been proposed for this disease so far, there is no definitive treatment.
Cite this article as: Ün M, Durmaz OB, Köylüoğlu E. Epidermodysplasia Verruciformis. JEB Med Sci 2020;1(1):42-45.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.