Elif Akbulut1, İlayda Üzümcü1, Aylin Kayaaltı1, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Turkey

Keywords: Clostridium difficile, depression, fecal microbiota transplantation, neurological disorders

Abstract

Fecal microbiota transplantation (FMT), also known as fecal bacteriotherapy, fecal transfusion, and stool transplantation, is considered to be one of the remarkable treatments of the last century. Fecal microbiota transplantation is the process of filtering and diluting the stool from a healthy donor and placing it in the gastrointestinal tract of the recipient. It was first used orally in the fourth century, under the name of "Yellow Soup" in China for food poisoning and diarrhea. Recently, it has been widely used in various clinical situations, recurrent and resistant cases of Clostridium difficile bacterial infection. The purpose of the FMT procedure is to improve the intestinal flora by suppressing the deteriorated intestinal microbiota with a healthy bacterial community. In this review, how to treat diseases with FMT and the positive effects of this method on patients with neurological disorders, allergy and cancer were discussed.

Cite this article as:Akbulut E, Üzümcü İ, Kayaaltı, Erbaş O. Fecal Microbiota Transplantation: Impacts on Neurological Disorders, Allergies, and Cancer. JEB Med Sci 2021;2(3):420-429.

Conflict of Interest

The authors received no financial support for the research and/or authorship of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.