Interferon Regulatory Factors 4 (IRF4) Gene and Hair Graying
Burçin Aktaş1, Oytun Erbaş1,2
1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Turkey
2Department of Physiology, Medical Faculty of Demiroğlu Bilim University, Istanbul, Turkey
Keywords: Hair graying, interferon regulatory factor 4, repigmentation
Abstract
Hair graying is known as a natural part of the aging process. This aging process occurs with the graying of half of the hair at the age of 50 on average. There is another process that happens outside this natural process. The graying process that starts under the age of 20 on average is called Premature hair graying (PHG). There are many genetic and environmental factors that affect the graying process. In this review prepared, IRF4 (Interferon regulatory factor 4) gene, which is one of these factors and has many functions in the body, is focused on. In addition, other factors were also mentioned, and many studies carried out for hair repigmentation, which has the characteristics of treatment, were examined, and the obtained findings were shared.
Cite this article as: Aktaş B, Erbaş O. Interferon Regulatory Factors 4 (IRF4) Gene and Hair Graying. JEB Med Sci 2021;2(2):158-162.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.