Ayşe Yürekli1, Oytun Erbaş1,2

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Turkey
2Department of Physiology, Medical Faculty of Demiroğlu Bilim University, Istanbul, Turkey

Keywords: Cancer, immunosuppression, tumor


Cancer, thought to date back about 120,000 years ago, is described as an uncontrolled and abnormal growth of cells. The degradation of the cell mechanism due to chemical, radiation, or genetic factors is the cause of this uncontrolled development. The immune system helps our bodies combat cancer cells that develop out of control and cause damage to other tissues. However, the immune system's response to antigens is sometimes suppressed. Immunosuppression can be triggered by cellular processes or produced by the use of drugs in certain surgical cases, such as transplantation. The immune system tolerates certain tumors while remaining unprotected due to the suppression of cancer and the inability to completely express the response. In this case, the question arises whether a cure can be discovered by identifying the immune system's response mechanism using immunosuppressive drugs in this manner. In this review, the relationship between immunosuppression and cancer is discussed.

Cite this article as: Yürekli A, Erbaş O. Cancer and Immunosuppression. JEB Med Sci 2021;2(2):116-121.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.