Animal Models of Epilepsy
Melda Ateş1, Hilal Harman2
1Demiroğlu Bilim University, Faculty of Medicine, Istanbul, Turkey
2Istanbul Gelişim University, Faculty of Nutrition and Dietetics, Istanbul, Turkey
Keywords: Animal models, epilepsy, seizure
Abstract
Epilepsy is one of the most common neurological disorders globally, caused by abnormal excess or synchronous neuronal activity in the brain, causing recurrent seizures. Many studies are carried out to understand the pathophysiology of this disorder and develop anti-seizure drugs. In animals, spontaneous epileptic attacks can be formed by various chemical stimuli and electrical stimulation methods, as well as genetic animal models to mimic the state of epileptic seizures. Providing animal models that are clinically similar to the model of epilepsy in humans is essential in understanding epilepsy and pharmacological studies.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.