Chronic Infection and Carcinogenesis: The Contribution of Porphyromonas gingivalis to Cancer Risk
Zeynep Nur Çetin1, Oytun Erbaş1
1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Türkiye
Keywords: Inflammation, cancer, Porphyromonas gingivalis.
Abstract
Porphyromonas gingivalis (P. gingivalis) is recognized as one of the most significant pathogens within the oral microbiota, which is directly associated with periodontal diseases, such as gingivitis and periodontitis. This bacterium is classified as an anaerobic, gram-negative organism. The capacity of P. Gingivalis to produce and release various toxins further reinforces its association with numerous diseases. In recent years, the proposition of a relationship between this bacterium and certain forms of cancer has emerged. The present review aims to evaluate the existing literature that investigates the correlation between various types of cancer and P. Gingivalis.
Cite this article as: Çetin ZN, Erbaş O. Chronic Infection and Carcinogenesis: The Contribution of Porphyromonas gingivalis to Cancer Risk. JEB Med Sci 2025;6(1):34-38.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.