Sıdıka Açıkgöz1, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Türkiye

Keywords: 3D cell culture, embryonic stem cells, extracellular matrix, stem cell, organoids.


In cell culture applications, modeling cells from the original tissue in culture medium has been difficult due to limitations in cell proliferation and differentiation. These limitations have directed researchers toward the discovery of organoid systems that better represent cells from the original tissue biologically, physiologically, and functionally in the culture medium. Organoid cultures can be formed from embryonic stem cells, induced pluripotent stem cells, or adult stem cells. They play a crucial role in various fields such as biology, medicine, and stem cell biology. This chapter reports on the areas of study, advantages, and disadvantages of organoid systems.

Cite this article as: Açıkgöz S, Erbaş O. Organoid Systems. JEB Med Sci 2024;5(1):33-38.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.