Büşra Nur Barmanbay1, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Türkiye

Keywords: Embryonic stem cells, hematopoietic stem cells, longterm hematopoietic stem cells, mesenchymal stem cells, short-term hematopoietic stem cells.


Hematopoietic stem cells (HSCs) are cells that can differentiate into any type of blood cell and can keep on making blood for the rest of a person's life. There is a role of HSCs in blood production and in many cellular processes such as apoptosis, calcium balance, mitochondria, and reactive oxygen species production. Mutations originating in HSCs)underlie genetic blood diseases. Additionally, HSCs are subject to the effects of aging, impairing their ability to maintain cell polarity. In this chapter, we extensively examined the characteristics and implications of HSCs.

Cite this article as: Barmanbay BN, Erbaş O. Hematopoietic Stem Cells. JEB Med Sci 2024;5(1):12-18.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.


The Figures (Figure 1 and Figure 2) used in this chapter were created with BioRender (BioRender.com).