Büşra Alan1, Ayşe Safiye Genç1, Oytun Erbaş1

1ERBAS Institute of Experimental Medicine, Illinois, USA & Gebze, Türkiye

Keywords: In vitro fertilization, infertility, platelet concentrate, platelet-rich plasma application


Over the years, the number of people suffering from infertility has increased globally. Individualized therapies are used in infertility therapy, unlike in other medical disciplines. Infertility instances might be of female or male origin, or both female and male origin, with the etiology of certain cases unexplained. Supportive therapy is utilized in individuals who have a poor ovarian response, have had several unsuccessful cycles, or are undiagnosed. The platelet-rich plasma (PRP) technique promotes cell proliferation by using the growth factors found in platelets. While the PRP approach is actively employed in a variety of industries, it is currently being used as an adjunct therapy in assisted reproductive procedures. Nonetheless, as this is a relatively novel application, there is ongoing contention regarding the standardization of PRP preparation methods, the frequency of its administration to patients, and the question of its effectiveness as a beneficial treatment. As a consequence of this analysis, it is believed that further prospective randomized clinical trials are required before PRP can be classified as a therapy. This review will explore the advantages and disadvantages of employing PRP for addressing endometrial receptivity and managing premature ovarian failure.

Cite this article as: Alan B, Genç AS, Erbaş O. Innovative Approach: Platelet-Rich Plasma and In Vitro Fertilization. JEB Med Sci 2023;4(2):110-115.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.


The Figures (Figure 1 and Figure 2) used in this review were created with BioRender (BioRender.com).